281-543-5251 | Contact Us 2401 Fountain View Dr, Ste 312 PMB 12, Houston, TX 77057
Donate

Knuckling Up for Brain Aneurysms, AVMs & Hemorrhagic Strokes
  • Give
    • Apparel
    • Other Ways to Give
    • GIVING
    • Gifts in Honor
  • About Us
    • Staff
    • Board of Directors
    • Medical Advisory Board
    • Our Mission
    • Partners
    • Contact Us
  • Education
    • Understanding
      • Brain Basics
      • What is an Aneurysm?
      • What is an AVM?
      • What is a Hemorrhagic Stroke?
      • Types of Cerebral Aneurysms
      • Factors of a Brain Aneurysm
      • Symptoms of a Brain Aneurysm
      • Dangers of a Brain Aneurysm
      • How Does a Brain Aneurysm Develop?
      • What Happens When an Aneurysm Bleeds?
      • How is a Brain Aneurysm Diagnosed?
    • Treatment
      • Unruptured Aneurysm
      • Ruptured Aneurysm
      • Clipping
      • Occlusion and Bypass
      • Endovascular Embolization / Coiling
      • Flow Diversion
      • Onyx Liquid Embolic System
      • Gamma Knife
      • Questions to Ask Your Doctor
      • Should I Get a Second Opinion?
      • Treating Physicians
  • Support
    • Support Groups
      • Support Group Locations
    • Recovery
      • Denial
      • Anger and Frustration
      • Depression
      • Bargaining
      • Acceptance
      • Post Recovery Issues
    • Caregivers
      • What a Caregiver Needs to Know
      • Recharging and Finding Balance
      • Looking After Yourself
    • What to Expect
  • Connect
    • Contact Us
    • Social Media
      • Facebook
        • Patients Online Support Group
        • Caregivers Online Support Group
        • Young Adult Online Survivor’s Support Group
        • Parents Online Support Group
        • Honoring the Taken Online Support Group
      • Twitter
      • Instagram
      • YouTube
      • LinkedIn
    • Stories
      • Survivors Around the Globe
      • The Caregiver’s Side
      • Honoring the Taken
      • Submit Your Story
    • Webinars
    • Blog
    • Knuckle Up Newsletter
  • Events
    • Knuckle Ball 2023
    • 2022 Virtual 5K: Walk. Run. Row. Cycle.
  • Grants
    • Joe Niekro Research Grant
      • Letter of Intent
      • Grant Application
      • Grant Recipients
    • Joe Niekro/SNIS Research Grant
    • Joe Niekro Patient’s Choice Award
    • Joe Niekro Crystal Bat Award
Home > Blog > Aneurysms > Groundbreaking Study Confirms That Neurointerventional Surgery Provides Significant Clinical Benefit
  • https://www.joeniekrofoundation.com/aneurysms/groundbreaking-study-confirms-that-neurointerventional-surgery-provides-significant-clinical-benefit/

    Groundbreaking Study Confirms That Neurointerventional Surgery Provides Significant Clinical Benefit

    Study is most significant stroke treatment clinical trial since NINDS-2 says Society of NeuroInterventional Surgery

    WASHINGTON, DC – December 17, 2014 – A new study published in the New England Journal of Medicine confirms that the addition of inside-the-artery clot removal is more effective than IV-administered “clot-busting” tissue plasminogen activator (IV-tPA) therapy alone for the treatment of stroke. These endovascular (or neurointerventional) procedures have potential life-saving benefits for almost 300,000 people in the United States who suffer a stroke with a large vessel blockage, says the Society of NeuroInterventional Surgery (SNIS).

    Of 695,000 people who suffer acute ischemic stroke in the U.S., 40 percent have a large-vessel blockage, which often leads to death or permanent disability. MR CLEAN (Multicenter Randomized Clinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands) evaluated the effect of endovascular treatment for patients with acute ischemic stroke caused by a clot obstructing one of the major intracranial arteries. The study showed that inside-the-artery clot removal during early treatment nearly doubled the likelihood of a good neurological outcome and that it worked well for patients who had received IV-tPA and for those who had contra-indications for IV-tPA.

    “The MR CLEAN Study confirms what we are seeing in everyday practice,” said Peter Rasmussen, MD, director of the Cerebrovascular Center, Cleveland Clinic in Cleveland, Ohio, and president of SNIS, “Within-the-artery procedures, which are performed by neurointerventional surgeons, are not the appropriate treatment for every patient suffering from stroke, but for many patients they are life-saving, viable and effective therapies that offer many benefits over traditional treatments, including shorter recovery times and a better chance to return to normal activities.”

    According to Dr. Donald Frei, a neurointerventional surgeon at Radiology Imaging Associates in Denver, Colo., and president-elect of SNIS, MR CLEAN is the most significant randomized, controlled stroke treatment study since the NINDS-2 trial in 1995 and subsequent FDA approval of IV-tPA. While IV-tPA revolutionized stroke care, it must be administered within 4.5 hours. Neurointerventional surgery can be performed up to 6 hours from the onset of stroke, significantly expanding the treatment window.

    “MR CLEAN is an important milestone in the transformation of care for stroke patients, but it is not the end of the story,” said Dr. Frei. “Neurointerventional surgery is a relatively young and rapidly changing field that typically outpaces clinical research, and we need to ensure that these treatments—their success evident in thousands of lives saved—continue to be evaluated in clinical trials. We are confident that when designed and implemented correctly, clinical studies will continue to show positive results.”

    Frei also said that neurointerventional surgery is a critical piece of a system of stroke care that has helped reduce death rates from stroke by more than 35 percent from 2000 to 2010. This includes public education to reduce risk factors and recognize the symptoms of stroke, emergency medical services processes and protocols to appropriately assess patients and emergency transport guidelines that immediately get stroke patients to a hospital that is equipped to provide the best evidence-based interventions for ischemic and hemorrhagic stroke management.

    SNIS works to develop general standards to define principles of practice that will produce high quality care and provides guidance on standardized techniques, procedures and practices in the neurointerventional field, not only to improve health care outcomes but also to define the core practice from which this specialty can build and grow.

    Stroke is the leading cause of disability and the fourth cause of death in U.S. In 2010, stroke cost the U.S. an estimated $54 billion, including the cost of healthcare services, medications and missed days of work. Strokes cost $74 billion in healthcare expenditures annually for treatment due to disability.

    For complete article, click here.

    Posted on Wednesday, December 17, 2014
  •  

    Comments

Common Questions

  • What is a brain aneurysm?
  • What is an AVM?
  • What is a hemorrhagic stroke?
  • What are the risk factors of a brain aneurysm?
  • What are the symptoms of a brain aneurysm?
  • What are the dangers of a brain aneurysm?
  • How does a brain aneurysm develop?
  • How is a brain aneurysm diagnosed?

Upcoming Events

  • Knuckle Ball 2023
  • 2022 Virtual 5K: Walk. Run. Row. Cycle.

News Room

  • Stories
  • Videos
  • Knuckle Up Newsletter

Connect with Us

  • Subscribe to our Knuckle-Up Newsletter
  • Become a Fan on Facebook
  • Follow us on Twitter
  • Follow us on Instagram
  • Join our Online Aneurysm/AVM Support Group
  • Join our Online Parents Support Group
  • Join our Online Young Adult Survivor’s Support Group
  • Join our Online Aneurysm/AVM Caregivers Support Group
  • Join our Online Honoring the Taken Support Group
  • Support Group Locations
  • Contact Us
  • References
  • Privacy Policy
© 2023 Joe Niekro Foundation. All Rights Reserved.
  • Donate

    Every donation matters - every dollar counts. The Joe Niekro Foundation is a registered 501 (c)(3) which means your donations are 100% tax deductible. Your donations are used to enhance the research and treatment of brain aneurysms, AVM and hemorrhagic strokes, while supporting patients and families through the recovery process.

    Donate Now!
  • Newsletter Sign Up

    The best way to keep up to date on all the JNF happenings. Sign up today for our Knuckle Up Newsletter!