281-543-5251 | Contact Us 2401 Fountain View Dr, Ste 312 PMB 12, Houston, TX 77057
Donate

Knuckling Up for Brain Aneurysms, AVMs & Hemorrhagic Strokes
  • Give
    • Apparel
    • Other Ways to Give
    • GIVING
    • Gifts in Honor
  • About Us
    • Staff
    • Board of Directors
    • Medical Advisory Board
    • Our Mission
    • Partners
    • Contact Us
  • Education
    • Understanding
      • Brain Basics
      • What is an Aneurysm?
      • What is an AVM?
      • What is a Hemorrhagic Stroke?
      • Types of Cerebral Aneurysms
      • Factors of a Brain Aneurysm
      • Symptoms of a Brain Aneurysm
      • Dangers of a Brain Aneurysm
      • How Does a Brain Aneurysm Develop?
      • What Happens When an Aneurysm Bleeds?
      • How is a Brain Aneurysm Diagnosed?
    • Treatment
      • Unruptured Aneurysm
      • Ruptured Aneurysm
      • Clipping
      • Occlusion and Bypass
      • Endovascular Embolization / Coiling
      • Flow Diversion
      • Onyx Liquid Embolic System
      • Gamma Knife
      • Questions to Ask Your Doctor
      • Should I Get a Second Opinion?
      • Treating Physicians
  • Support
    • Support Groups
      • Support Group Locations
    • Recovery
      • Denial
      • Anger and Frustration
      • Depression
      • Bargaining
      • Acceptance
      • Post Recovery Issues
    • Caregivers
      • What a Caregiver Needs to Know
      • Recharging and Finding Balance
      • Looking After Yourself
    • What to Expect
  • Connect
    • Contact Us
    • Social Media
      • Facebook
        • Patients Online Support Group
        • Caregivers Online Support Group
        • Young Adult Online Survivor’s Support Group
        • Parents Online Support Group
        • Honoring the Taken Online Support Group
      • Twitter
      • Instagram
      • YouTube
      • LinkedIn
    • Stories
      • Survivors Around the Globe
      • The Caregiver’s Side
      • Honoring the Taken
      • Submit Your Story
    • Webinars
    • Blog
    • Knuckle Up Newsletter
  • Events
    • Knuckle Ball 2023
    • 2022 Virtual 5K: Walk. Run. Row. Cycle.
  • Grants
    • Joe Niekro Research Grant
      • Letter of Intent
      • Grant Application
      • Grant Recipients
    • Joe Niekro/SNIS Research Grant
    • Joe Niekro Patient’s Choice Award
    • Joe Niekro Crystal Bat Award
Home > Blog > Aneurysms > Measuring Unruptured Aneurysms
  •  

    Measuring Unruptured Aneurysms

    This novel study established a new standard for the measurement of aneurysm treatment success, target aneurysm recurrence rate, and proves that coiling in an excellent treatment for ruptured and unruptured aneurysms.

    Begun in 2007, the MAPS trial is the largest, most rigorous randomized controlled study to-date on the clinical effectiveness of coils for treating both ruptured and unruptured aneurysms, which are estimated to affect approximately 5% of the population. Designed and led by Principal Investigators S. Claiborne Johnston, M.D., Ph.D., Cameron McDougall, M.D., and Anil Gholkar, O.B.E., M.B.B.S., the trial examined 626 patients worldwide with a single aneurysm.

    Implanted in more than 250,000 patients worldwide, GDC Detachable Coils are made of very soft platinum wire and were the first coils cleared by the FDA for the minimally invasive treatment of brain aneurysms in 1995.  Cleared in 2002, Matrix2 Detachable Coils incorporate a PGLA polymer on the outside of a traditional platinum coil that is designed to degrade over time and promote rapid tissue development within the aneurysm.

    Matrix Coils employ a proprietary outer copolymer coil over an inner platinum main coil. The copolymer runs the entire length of the main coil and constitutes approximately 70% of total coil volume.

    “While the neurovascular specialty commonly measures aneurysm treatment success with angiographic images, we believe success should be more closely aligned with patients’ clinical outcomes,” Mark Paul, president of Stryker Neurovascular, was quoted as saying. “The MAPS Trial demonstrates the validity of TAR as a clinical endpoint and proves aneurysm coiling is a very effective therapy with excellent clinical outcomes.”

    In the trial, 96% of patients with unruptured aneurysms and 90% of patients with acutely ruptured aneurysms were alive and free of disability out to 15 months after treatment. Trial results also demonstrate that, overall, Matrix2 Detachable Coils are as effective as GDC Detachable Coils (TAR rates of 13.3% vs. 14.6%, respectively).  In aneurysms with good occlusion (minimal blood flow entering the aneurysm) immediately post procedure, Matrix2 Detachable Coils demonstrate a statistically significant, superior long-term TAR rate of 2.7% compared to GDC Detachable Coils (9.6%).

    SOURCE: Society of NeuroInterventional Surgery (SNIS) 8th Annual Meeting in Colorado Springs

     

    Posted on Tuesday, September 6, 2011
  •  

    Comments

Common Questions

  • What is a brain aneurysm?
  • What is an AVM?
  • What is a hemorrhagic stroke?
  • What are the risk factors of a brain aneurysm?
  • What are the symptoms of a brain aneurysm?
  • What are the dangers of a brain aneurysm?
  • How does a brain aneurysm develop?
  • How is a brain aneurysm diagnosed?

Upcoming Events

  • Knuckle Ball 2023
  • 2022 Virtual 5K: Walk. Run. Row. Cycle.

News Room

  • Stories
  • Videos
  • Knuckle Up Newsletter

Connect with Us

  • Subscribe to our Knuckle-Up Newsletter
  • Become a Fan on Facebook
  • Follow us on Twitter
  • Follow us on Instagram
  • Join our Online Aneurysm/AVM Support Group
  • Join our Online Parents Support Group
  • Join our Online Young Adult Survivor’s Support Group
  • Join our Online Aneurysm/AVM Caregivers Support Group
  • Join our Online Honoring the Taken Support Group
  • Support Group Locations
  • Contact Us
  • References
  • Privacy Policy
© 2023 Joe Niekro Foundation. All Rights Reserved.
  • Donate

    Every donation matters - every dollar counts. The Joe Niekro Foundation is a registered 501 (c)(3) which means your donations are 100% tax deductible. Your donations are used to enhance the research and treatment of brain aneurysms, AVM and hemorrhagic strokes, while supporting patients and families through the recovery process.

    Donate Now!
  • Newsletter Sign Up

    The best way to keep up to date on all the JNF happenings. Sign up today for our Knuckle Up Newsletter!